Drivers faced delays after one lane of the A420 westbound carriageway closed after an accident between Oxford and Swindon.
Thames Valley Police officers were called at 3.30pm on Saturday after a car came off the road.
Motorists faced delays after a lane was closed at the junction with the A415 in Kingston Bagpuize while the route was cleared.
Thames Valley Police spokeswoman Francine Rodrigues said no one was hurt.
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